BDBM50325165 5-methyl-8-(4-((methylamino)methyl)phenyl)-[1,2,4]triazolo[4,3-a]quinolin-1(2H)-one::CHEMBL1223388

SMILES CNCc1ccc(cc1)-c1ccc2c(C)cc3n[nH]c(=O)n3c2c1

InChI Key InChIKey=JGWGGEAYCCMUQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325165   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50325165(5-methyl-8-(4-((methylamino)methyl)phenyl)-[1,2,4]...)
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-CHK1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed