BDBM50325153 CHEMBL1223245::N-methyl-4-(5-methyl-1-oxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinolin-8-yl)benzamide

SMILES CNC(=O)c1ccc(cc1)-c1ccc2c(C)cc3n[nH]c(=O)n3c2c1

InChI Key InChIKey=PQAXOSDTZBEMPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325153   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50325153(N-methyl-4-(5-methyl-1-oxo-1,2-dihydro-[1,2,4]tria...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-CHK1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed