BDBM50325018 (5R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(2'-(1-methyl-1H-tetrazol-5-yl)biphenyl-4-yl)imidazolidine-2,4-dione::CHEMBL1223224

SMILES Cn1nnnc1-c1ccccc1-c1ccc(cc1)[C@]1(CN2Cc3ccc(F)cc3C2=O)NC(=O)NC1=O

InChI Key InChIKey=AQOFRQLPFVJDJX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325018   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325018((5R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataKi:  10nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed