BDBM50325015 (R)-5-(4'-(1H-pyrazol-3-yl)biphenyl-4-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1223154

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)-c3cc[nH]n3)C(=O)c2c1

InChI Key InChIKey=SMFXJQFOJPRACG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325015   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325015((R)-5-(4'-(1H-pyrazol-3-yl)biphenyl-4-yl)-5-((6-me...)
Affinity DataKi:  2nMAssay Description:Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed