BDBM50324861 CHEMBL1221449::Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4-methyl-piperazin-1-yl)-phenyl]-amide

SMILES CN1CCN(CC1)c1cccc(c1)N(CC1CC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=PLVZHOWVQHWPON-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50324861   

Target5-hydroxytryptamine receptor 6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 88nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 672nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 1.43E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 3.04E+3nMAssay Description:Displacement of [3H]LSD from human 5HT7 expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50324861(Naphthalene-2-sulfonicacid cyclopropylmethyl-[3-(4...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C expressed in CHOKI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed