BDBM50324688 CHEMBL1221700::N-(4-(4-tert-butylphenylamino)quinazolin-6-yl)acrylamide

SMILES CC(C)(C)c1ccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)cc1

InChI Key InChIKey=FNFJNUTXQRGXER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324688   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50324688(N-(4-(4-tert-butylphenylamino)quinazolin-6-yl)acry...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of c-src in by radioactive phosphotransfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50324688(N-(4-(4-tert-butylphenylamino)quinazolin-6-yl)acry...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of Fyn expressed in Escherichia coli C43 by radioactive phosphotransfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50324688(N-(4-(4-tert-butylphenylamino)quinazolin-6-yl)acry...)
Affinity DataIC50: 689nMAssay Description:Inhibition of human recombinant EGFR expressed in baculovirus-infected Sf9 cells by radioactive phosphotransfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed