BDBM50324616 4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine::CHEMBL1215732

SMILES Fc1cccc(c1)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=NDUUGOAGHNLAIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324616   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50: 386nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50: 928nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50: 515nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324616(4-(4'-Fluoro-biphenyl-4-ylmethyl)pyridine | CHEMBL...)
Affinity DataIC50: 668nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed