BDBM50324612 4'-(Pyridin-4-ylmethyl)biphenyl-4-amine::CHEMBL1215665

SMILES Nc1ccc(cc1)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=DFRORZVGCQQRJH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324612   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50: 408nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50: 522nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50: 406nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50324612(4'-(Pyridin-4-ylmethyl)biphenyl-4-amine | CHEMBL12...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed