BDBM50324599 (R)-N-(4-(1H-Pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxamide::CHEMBL1215305

SMILES COc1ccc2CN[C@H](Cc2c1)C(=O)Nc1ccc(cc1OCCN1CCCC1)-c1cn[nH]c1

InChI Key InChIKey=FYHNIUJJYVTXSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324599   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324599((R)-N-(4-(1H-Pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324599((R)-N-(4-(1H-Pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50: 218nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed