BDBM50324527 4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobutanoic Acid Hydrochloride::CHEMBL1215587

SMILES CN(C)CCCCCCCCN(O)C(=O)CCC(O)=O

InChI Key InChIKey=FKNFFLDUNDBHGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324527   

TargetLysine-specific demethylase 4A(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PHD2 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed