BDBM50324368 4-Phenylsulfonylfuroxan-3-carbonitrile::CHEMBL1215577

SMILES [O-][n+]1onc(c1C#N)S(=O)(=O)c1ccccc1

InChI Key InChIKey=SFPIYSHETFEEQG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324368   

TargetMultidrug resistance-associated protein 1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324368(4-Phenylsulfonylfuroxan-3-carbonitrile | CHEMBL121...)
Affinity DataEC50:  7.20E+4nMAssay Description:Induction of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324368(4-Phenylsulfonylfuroxan-3-carbonitrile | CHEMBL121...)
Affinity DataEC50:  5.54E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed