BDBM50324357 4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide::CHEMBL1215509

SMILES NS(=O)(=O)c1c(no[n+]1[O-])-c1ccccc1

InChI Key InChIKey=DSSZDNBKKXDICA-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50324357   

TargetMultidrug resistance-associated protein 1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human CA9 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of human CA12 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  49nMAssay Description:Inhibition of human CA2 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324357(4-phenyl-3-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  57nMAssay Description:Inhibition of human CA1 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed