BDBM50324356 3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide::CHEMBL1215508

SMILES NS(=O)(=O)c1no[n+]([O-])c1-c1ccccc1

InChI Key InChIKey=URWBEJZZFHZFJY-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50324356   

TargetMultidrug resistance-associated protein 1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human CA9 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  9.90nMAssay Description:Inhibition of human CA12 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  38nMAssay Description:Inhibition of human CA2 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50324356(3-phenyl-4-sulfamoyl-1,2,5-oxadiazole 2-oxide | CH...)
Affinity DataKi:  42nMAssay Description:Inhibition of human CA1 by CO2 hydration activity based stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed