BDBM50324298 CHEMBL1215712::{4-[1-(4-Isobutylpiperazin-1-yl)[2,6]naphthyridin-3-yl]pyridin-2-yl}(tetrahydropyran-4-yl)amine

SMILES CC(C)CN1CCN(CC1)c1nc(cc2cnccc12)-c1ccnc(NC2CCOCC2)c1

InChI Key InChIKey=PQIBJTXBLUQNSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324298   

TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324298({4-[1-(4-Isobutylpiperazin-1-yl)[2,6]naphthyridin-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324298({4-[1-(4-Isobutylpiperazin-1-yl)[2,6]naphthyridin-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of PKD1 assessed as HDAC5 neuclear exportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed