BDBM50324159 CHEMBL1215551::Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,6-dimethyl-2-(trifluoromethyl)-1,4-dihydropyridine-3-carboxylate

SMILES COC(=O)C1=C(N(C)C(C)=C(C#N)C1c1ccc(F)cc1Cl)C(F)(F)F

InChI Key InChIKey=BAVATTCEWXIPMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324159   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324159(Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,6-dim...)
Affinity DataIC50: 275nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed