BDBM50324090 CHEMBL1214959::N-(Benzofuran-2-ylmethyl)-N'-(3'-propoxybenzyl)piperazine

SMILES CCCOc1cccc(CN2CCN(Cc3cc4ccccc4o3)CC2)c1

InChI Key InChIKey=CZPHWPDUDLEVFW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324090   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324090(N-(Benzofuran-2-ylmethyl)-N'-(3'-propoxybenzyl)pip...)
Affinity DataKi:  177nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324090(N-(Benzofuran-2-ylmethyl)-N'-(3'-propoxybenzyl)pip...)
Affinity DataKi:  259nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324090(N-(Benzofuran-2-ylmethyl)-N'-(3'-propoxybenzyl)pip...)
Affinity DataKi:  774nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50324090(N-(Benzofuran-2-ylmethyl)-N'-(3'-propoxybenzyl)pip...)
Affinity DataKi:  2.98E+3nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed