BDBM50323922 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)urea::CHEMBL1213924

SMILES Cc1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=VZONEKWHHXKRRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323922   

TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50: 18.4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed