BDBM50323832 CHEMBL1214267::N-(5-(trifluoromethyl)pyridin-2-yl)-7-(5-(trifluoromethyl)pyrimidin-4-yl)-1,8-naphthyridin-4-amine

SMILES FC(F)(F)c1ccc(Nc2ccnc3nc(ccc23)-c2ncncc2C(F)(F)F)nc1

InChI Key InChIKey=DMVWXWJLDQNRIM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323832   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50323832(N-(5-(trifluoromethyl)pyridin-2-yl)-7-(5-(trifluor...)Copy SMILESCopy InChI

Affinity DataIC50: 134nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2011
Entry Details Article
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