BDBM50323827 5-(trifluoromethyl)-2-(7-(3-(trifluoromethyl)pyridin-2-yl)-1,8-naphthyridin-4-ylamino)pyrimidine-4-carboxamide::CHEMBL1214208

SMILES NC(=O)c1nc(Nc2ccnc3nc(ccc23)-c2ncccc2C(F)(F)F)ncc1C(F)(F)F

InChI Key InChIKey=SQRKNQWEMACXHS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323827   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50323827(5-(trifluoromethyl)-2-(7-(3-(trifluoromethyl)pyrid...)Copy SMILESCopy InChI

Affinity DataIC50: 49nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2011
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL