BDBM50323825 CHEMBL1214206::N-(4-chloro-5-(trifluoromethyl)pyrimidin-2-yl)-7-(3-(trifluoromethyl)pyridin-2-yl)-1,8-naphthyridin-4-amine

SMILES FC(F)(F)c1cnc(Nc2ccnc3nc(ccc23)-c2ncccc2C(F)(F)F)nc1Cl

InChI Key InChIKey=ZEEMBWAWUBDSHE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323825   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Neurogen

Curated by ChEMBL

LigandBDBM50323825(N-(4-chloro-5-(trifluoromethyl)pyrimidin-2-yl)-7-(...)Copy SMILESCopy InChI

Affinity DataIC50: 81nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2011
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL