BDBM50323724 CHEMBL1213660::S-phenyl 3-(4-hydroxy-3,5-dimethylstyryl)benzothioate

SMILES Cc1cc(\C=C\c2cccc(c2)C(=O)Sc2ccccc2)cc(C)c1O

InChI Key InChIKey=FXFWECMBRQGCCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323724   

TargetTransthyretin(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323724(S-phenyl 3-(4-hydroxy-3,5-dimethylstyryl)benzothio...)
Affinity DataIC50: 2.00E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed