BDBM50323711 (1R,2R,3S,4S,5R,6S)-5-(2-aminoethoxy)-3,6-dihydroxycyclohexane-1,2,4-triyl triphosphate::CHEMBL1213202

SMILES NCCO[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=GPBLFCGWVORRDU-UHFFFAOYSA-N

Data  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323711   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323711((1R,2R,3S,4S,5R,6S)-5-(2-aminoethoxy)-3,6-dihydrox...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at rat recombinant IP3R1 expressed in chicken DT40 cells assessed as calcium release from intracellular storesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323711((1R,2R,3S,4S,5R,6S)-5-(2-aminoethoxy)-3,6-dihydrox...)
Affinity DataKd:  43.6nMAssay Description:Displacement of [3H]IP3 from full-length rat recombinant IP3R1 expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323711((1R,2R,3S,4S,5R,6S)-5-(2-aminoethoxy)-3,6-dihydrox...)
Affinity DataKd:  13.5nMAssay Description:Displacement of [3H]IP3 from rat recombinant N-terminal IP3R1 (1-604) expressed in chicken DT40 cells by equilibrium competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50323711((1R,2R,3S,4S,5R,6S)-5-(2-aminoethoxy)-3,6-dihydrox...)
Affinity DataKd:  0.520nMAssay Description:Displacement of [3H]IP3 from rat recombinant IP3R1 binding core residue (224-604) expressed in chicken DT40 cells by equilibrium competitive binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed