BDBM50323581 4-(2-(pyridin-2-yl)vinyl)pyrimidin-2-amine::CHEMBL1209743

SMILES Nc1nccc(\C=C\c2ccccn2)n1

InChI Key InChIKey=YMGNNTVWSYKAPY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323581   

TargetMetabotropic glutamate receptor 4(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50323581(4-(2-(pyridin-2-yl)vinyl)pyrimidin-2-amine | CHEMB...)
Affinity DataEC50:  1.17E+4nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO-K1 cells assessed as decrease in forskolin-induced intracellular cAMP accumulation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed