BDBM50323565 4-(phenylethynyl)pyrimidin-2-amine::CHEMBL1209591

SMILES Nc1nccc(n1)C#Cc1ccccc1

InChI Key InChIKey=KDDLLSWPVURFDD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323565   

TargetMetabotropic glutamate receptor 4(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50323565(4-(phenylethynyl)pyrimidin-2-amine | CHEMBL1209591)
Affinity DataEC50:  2.00E+4nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO-K1 cells assessed as decrease in forskolin-induced intracellular cAMP accumulation af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed