BDBM50323483 CHEMBL1209285::N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(3-(3-oxo-1,4-oxazepan-4-yl)phenyl)cyclohexylamino)butan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cccc(c1)N1CCCOCC1=O

InChI Key InChIKey=PCWSXIPKKVFNIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323483   

TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50323483(N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(...)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant BACE-1 expressed in Escherichia coli after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed