BDBM50323460 CHEMBL1209885::N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide

SMILES Oc1ccc(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O

InChI Key InChIKey=SYNDQCRDGGCQRZ-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323460   

TargetDynamin-1(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50323460(N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthoh...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of GTPase activity of Dynamin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50323460(N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthoh...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50323460(N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthoh...)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed