BDBM50323451 CHEMBL1209794::N-(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidine-3-carbonyl)-5-methyl-3H-spiro[isobenzofuran-1,4'-piperidine]-3-yl)propan-2-yl)acetamide

SMILES CC(=O)NC(C)(C)[C@H]1OC2(CCN(CC2)C(=O)[C@@H]2CN(C[C@H]2c2ccc(F)cc2F)C2CCOCC2)c2cc(Cl)c(C)cc12

InChI Key InChIKey=YYCCWOBZNRVRNZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323451   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323451(N-(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophen...)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at human melanocortin 4 receptor expressed in CHO cells assessed as cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323451(N-(2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophen...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed