BDBM50323319 3-(3-(carbamoyl)benzamido)-3-(4-methoxyphenyl)propanoic acid::3-(4-methoxyphenyl)-3-(3-(1,2,3,4-tetrahydroisoquinolin-7-ylcarbamoyl)benzamido)propanoic acid::CHEMBL218963

SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1

InChI Key InChIKey=VHKHAQYPTPVIAP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323319   

TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323319(3-(4-methoxyphenyl)-3-(3-(1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetIntegrin alpha-3/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323319(3-(4-methoxyphenyl)-3-(3-(1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrin alpha-3/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50323319(3-(4-methoxyphenyl)-3-(3-(1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed