BDBM50323210 2,3-dihydroamentoflavone::CHEMBL220741

SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)[C@@H]3CC(=O)c4c(O)cc(O)cc4O3)c2o1

InChI Key InChIKey=JVBCTBWKMWXQQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323210   

TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323210(2,3-dihydroamentoflavone | CHEMBL220741)
Affinity DataIC50: 750nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50323210(2,3-dihydroamentoflavone | CHEMBL220741)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed