BDBM50323202 4',7''-O-methylamentoflavone::4',7''-di-O-methyl-amentoflavone::4',7''-di-O-methylamentoflavone::CHEMBL208988

SMILES COc1ccc(cc1-c1c(OC)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1)-c1cc(O)c2c(cc(O)cc2=O)o1

InChI Key InChIKey=ZQAIYKCPFGBVKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323202   

TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323202(4',7''-di-O-methyl-amentoflavone | 4',7''-di-O-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50323202(4',7''-di-O-methyl-amentoflavone | 4',7''-di-O-met...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed