BDBM50323198 4'''-methylamentoflavone::CHEMBL220745::podocarpusflavone A

SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1

InChI Key InChIKey=MDYSVIBQXPJGQJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323198   

TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 990nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 750nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed