BDBM50323197 7''-O-methylamentoflavone::CHEMBL450522::sotetsuflavone

SMILES COc1cc(O)c2c(oc(cc2=O)-c2ccc(O)cc2)c1-c1cc(ccc1O)-c1cc(O)c2c(cc(O)cc2=O)o1

InChI Key InChIKey=BMNIKONLDGLLMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50323197   

TargetBeta-secretase 1(Human)
Shujitsu University

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DENV C-terminal histidine-tagged NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed