BDBM50323168 (5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-methylimidazo[1,2-a]pyrimidin-6-yl)methanamine::CHEMBL1208901

SMILES COc1ccccc1-c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=AXPSSBPJXIUGGG-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50323168   

TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  9nMAssay Description:Inhibition of human DPP4 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  13nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  15nMAssay Description:Inhibition of human DPP4 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  15nMAssay Description:Inhibition of human DPP4 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  7.83E+3nMAssay Description:Inhibition of DPP8 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition of DPP8 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human DPP89More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DPP8 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323168((5-(2,4-dichlorophenyl)-2-(2-methoxyphenyl)-7-meth...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DPP9 after 15 mins by para-nitroaniline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed