BDBM50323161 (5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1,2-a]pyrimidin-6-yl)methanamine::CHEMBL1209853

SMILES Cc1nc2nc(cn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1ccccc1

InChI Key InChIKey=MMKVMFVAFDJNGK-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50323161   

TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50: 1.00E+3nMAssay Description:inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50: 4.00E+4nMAssay Description:inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50: 1.30E+4nMAssay Description:inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50: 1.90E+4nMAssay Description:inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi:  6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human DPP89More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed