BDBM50323139 (R)-(4-(4-(furan-2-yl)phthalazin-1-yl)-3-methylpiperazin-1-yl)(phenyl)methanone::CHEMBL1209315

SMILES C[C@@H]1CN(CCN1c1nnc(-c2ncco2)c2ccccc12)C(=O)c1ccccc1

InChI Key InChIKey=DZGXRDBKXVINBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323139   

TargetSmoothened homolog(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50323139((R)-(4-(4-(furan-2-yl)phthalazin-1-yl)-3-methylpip...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human Smo receptor in HEPM cells assessed as inhibition of Gli expression after 24 hrs by quantigene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed