BDBM50323019 4-[(1R,2R,6S,7S)-3,5-dioxo-9-propionyl-11-oxa-4,9-diazatricyclo[5.3.1.02,6]undec-4-yl]-2-(trifluoromethyl)benzonitrile::CHEMBL1209904

SMILES CCC(=O)N1C[C@]2(C)O[C@](C)(C1)c1c(O)n(c(O)c21)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=LOIDUXFBDLVTKC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323019   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323019(4-[(1R,2R,6S,7S)-3,5-dioxo-9-propionyl-11-oxa-4,9-...)
Affinity DataIC50: 129nMAssay Description:Antagonist activity at human wild type AR expressed in human MDA-MB-435 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323019(4-[(1R,2R,6S,7S)-3,5-dioxo-9-propionyl-11-oxa-4,9-...)
Affinity DataIC50: 549nMAssay Description:Antagonist activity at wild type human AR expressed in human LNCAP cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323019(4-[(1R,2R,6S,7S)-3,5-dioxo-9-propionyl-11-oxa-4,9-...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]DHT from AR in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed