BDBM50322990 CHEMBL1210082::rac-6-amino-N-(1-(3-ethoxy-4,5-difluorobenzyl)azepan-4-yl)nicotinamide

SMILES CCOc1cc(CN2CCCC(CC2)NC(=O)c2ccc(N)nc2)cc(F)c1F

InChI Key InChIKey=OMARKUBVZGBSTE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322990   

TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322990(rac-6-amino-N-(1-(3-ethoxy-4,5-difluorobenzyl)azep...)
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at human SST5 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322990(rac-6-amino-N-(1-(3-ethoxy-4,5-difluorobenzyl)azep...)
Affinity DataKi:  436nMAssay Description:Displacement of radio labeled 11 Tyr SST14 from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed