BDBM50322844 3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,7H)-dione::CHEMBL405901

SMILES CCCn1c(=O)n(CC)c2nc([nH]c2c1=O)-c1cn[nH]c1

InChI Key InChIKey=MVDURWNMLXKWGS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50322844   

TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  49nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]ZM-241385 from human recombinant adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  178nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  178nMAssay Description:Displacement of [3H]CPX from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  496nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50322844(3-ethyl-1-propyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6...)
Affinity DataKi:  496nMAssay Description:Displacement of [3H]ZM-241385 from human recombinant adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed