BDBM50322791 3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol::CHEMBL1173260

SMILES Oc1ccc(cc1F)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=SFFLHOMUFWFHRI-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50322791   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 186nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 896nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 186nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 351nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)
Affinity DataIC50: 896nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed