BDBM50322789 4'-(pyridin-4-ylmethyl)biphenyl-3-ol::4-[(3'-Hydroxybiphenyl-4-yl)methyl]pyridine::CHEMBL1172882

SMILES Oc1cccc(c1)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=GFIBJCSJSOCGMM-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50322789   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 342nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 261nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 663nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 538nMAssay Description:Inhibition of recombinant CYP3A4 expressed in baculovirus-infected insect microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 342nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 261nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 663nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)
Affinity DataIC50: 538nMAssay Description:Inhibition of CYP3A4 expressed in baculovirus infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed