BDBM50322785 4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine::CHEMBL1173327

SMILES Nc1ccc(cc1N)-c1ccc(Cc2ccncc2)cc1

InChI Key InChIKey=SRXFPSNWVWAMBL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50322785   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 337nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 902nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 367nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 337nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 502nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 368nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed