BDBM50322571 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide::CHEMBL1173200

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(CCc4cnc5cccnn45)c3)cc2C(F)(F)F)CC1

InChI Key InChIKey=PNIYZZGBJQTQKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322571   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322571(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethyl]-4-methyl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of wild type human ABL after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed