BDBM50322560 3-[2-(Imidazo[1,2-a]pyrimidin-3-yl)ethynyl]-4-methyl-N-{4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide::CHEMBL1171835

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ncccn34)cc2C(F)(F)F)CC1

InChI Key InChIKey=RVLFSNSFHXSXBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322560   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322560(3-[2-(Imidazo[1,2-a]pyrimidin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 69nMAssay Description:Inhibition of wild type human ABL after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed