BDBM50322539 3-{2-[8-(Acetylamino)imidazo-[1,2-a]pyridin-3-yl]ethynyl}-N-[3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methylbenzamide::CHEMBL1172585

SMILES CC(=O)Nc1cccn2c(cnc12)C#Cc1cc(ccc1C)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1ccnc1

InChI Key InChIKey=VMFUXAFEDBBWDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322539   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322539(3-{2-[8-(Acetylamino)imidazo-[1,2-a]pyridin-3-yl]e...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of wild type human ABL after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed