BDBM50322537 3-{2-[6-(Cyclopropylamino)purin-9-yl]ethynyl}-N-[5-(1,1-dimethylethyl)isoxazol-3-yl]-4-methylbenzamide::CHEMBL1171280

SMILES Cc1ccc(cc1C#Cn1cnc2c(NC3CC3)cccc12)C(=O)Nc1cc(on1)C(F)(F)F

InChI Key InChIKey=JKILJFCKZMHEPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322537   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322537(3-{2-[6-(Cyclopropylamino)purin-9-yl]ethynyl}-N-[5...)
Affinity DataIC50: 28nMAssay Description:Inhibition of wild type human ABL after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed