BDBM50322242 1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidin-4-ol oxalate::CHEMBL1170456

SMILES OC1(CCN(Cc2cc3ccccc3o2)CC1)c1ccc(I)cc1

InChI Key InChIKey=SBRNDJDCLNCYMZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322242   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322242(1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  1.41nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322242(1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  14.3nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322242(1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322242(1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidi...)
Affinity DataKi:  245nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed