BDBM50322234 8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate::CHEMBL1169728

SMILES CN1CN(c2ccccc2)C2(CCN(Cc3csc4ccccc34)CC2)C1=O

InChI Key InChIKey=BKMRLPDOTVKGIM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322234   

TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322234(8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-...)
Affinity DataKi:  60.1nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322234(8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-...)
Affinity DataKi:  71.4nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322234(8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-...)
Affinity DataKi:  331nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322234(8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-...)
Affinity DataKi:  352nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed