BDBM50322232 4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)piperidin-4-ol::CHEMBL1169904

SMILES COc1cccc2[nH]cc(CN3CCC(O)(CC3)c3ccc(Cl)cc3)c12

InChI Key InChIKey=HYRBVOGJRAFDLT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322232   

TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322232(4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322232(4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  250nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322232(4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)met...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50322232(4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)met...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed