BDBM50322162 CHEMBL1169707::N-Benzyl-N-methyl-3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine

SMILES CN(Cc1ccccc1)c1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=GCWNAFLHJNJVCV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322162   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322162(N-Benzyl-N-methyl-3-(phenylsulfonyl)thieno[2,3-e][...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322162(N-Benzyl-N-methyl-3-(phenylsulfonyl)thieno[2,3-e][...)
Affinity DataIC50: 5nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322162(N-Benzyl-N-methyl-3-(phenylsulfonyl)thieno[2,3-e][...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed