BDBM50322102 3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine::CHEMBL1172795

SMILES Clc1cccc(c1)S(=O)(=O)c1nnn2c3ccsc3c(NCc3cccnc3)nc12

InChI Key InChIKey=IJFVEGGGPIVAMP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322102   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322102(3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...)
Affinity DataIC50: 31.7nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322102(3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322102(3-(3-chlorophenylsulfonyl)-N-(pyridin-3-ylmethyl)t...)
Affinity DataKi:  14.7nMAssay Description:Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed